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Inhibitors for the Treatment of Human Disease. Cleave Biosciences is focused on mining novel targets in cellular protein homeostasis pathways as therapeutic targets in cancer and neurodegenerative diseases. 11162017 Ronan Le Moigne is lead author on the Molecular Cancer Therapeutics paper, The p97 Inhibitor CB-5083 is a Unique Disrupter of Protein Homeostasis in Models of Multiple Myeloma.
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See Ray039;s lectures on the ubiquitin system at iBioseminars !PARSED CONTENT
The web page had the following on the web page, "Protein Homeostasis and the Ubiquitin-Proteasome System." I saw that the web site said " See Rays lectures on the ubiquitin system at." They also said " Our passion is to understand the basic biology of protein homeostasis and how it relates to major human diseases. Three questions motivate our research. 1 How do cells maintain protein homeostasis? 2 How do changes in protein homeostasis lead to pathology? 3 Can modulation of protein homeostasis be used to treat disease? Back to top of page."SEE SUBSEQUENT BUSINESSES
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